Solutions for Life Science & Diagnostics
CXCR4 Monoclonal Antibody
Additional Information
CXCR4 Monoclonal Antibody Specifications
| Background: | The 12G5 mAb reacts with the chemokine receptor CXCR4, previously called Fusin or LESTER. CXCR4 is a seven transmembrane domain receptor, which is involved in the signaling of the chemokine, Stromal cell-derived factor-1 (SDF-1). SDF-1 is an efficacious chemoattractant for lymphocytes and monocytes but is inactive on neutrophils. CXCR4 expression on T cells and on macrophages and its absence on neutrophilic and eosinophilic granulocytes mirrors the chemotactic activity of SDF-1 for leukocyte subsets. The CXCR4 receptor was shown to serve as a cofactor for HIV-1 isolates that are tropic for T cell lines. |
| Clonality: | Monoclonal |
| Clone Number: | 12G5 |
| Host Species: | Mouse |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a k |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 0.5 mg |
| Species Reactivities: | H, mk |
| Status: | RUO |
| Storage: | -20 |
| Target: | CXCR4 |
Applications: FCM, IH
There are no references for CXCR4 Monoclonal Antibody at this time.
