Solutions for Life Science & Diagnostics

CXCR4 Monoclonal Antibody

Ordering Guide

SKUNameSizeQtyPriceAdd to Cart
AT-2007 CXCR4 Monoclonal Antibody 0.5 mg $596.18

Additional Information

CXCR4 Monoclonal Antibody Specifications

Background:The 12G5 mAb reacts with the chemokine receptor CXCR4, previously called Fusin or LESTER. CXCR4 is a seven transmembrane domain receptor, which is involved in the signaling of the chemokine, Stromal cell-derived factor-1 (SDF-1). SDF-1 is an efficacious chemoattractant for lymphocytes and monocytes but is inactive on neutrophils. CXCR4 expression on T cells and on macrophages and its absence on neutrophilic and eosinophilic granulocytes mirrors the chemotactic activity of SDF-1 for leukocyte subsets. The CXCR4 receptor was shown to serve as a cofactor for HIV-1 isolates that are tropic for T cell lines.
Clone Number:12G5
Host Species:Mouse
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Isotype:IgG2a k
Product Type:Primary Antibody
Size:0.5 mg
Species Reactivities:H, mk

Applications: FCM, IH

There are no references for CXCR4 Monoclonal Antibody at this time.