Angiogenesis
Apoptosis
Autophagy & Proteolysis
Cancer & Cell Proliferation
Cell Surface Antigens
Cellular Stress
Cytokines & Growth Factors
Epigenetics
Epitope Tags
Fluorescent Proteins
GPCR
In Vitro Diagnostics
Inflammation & Immunology
Metabolism
Molecular Biology
Neuroscience
Signal Transduction
Solute Carrier
Virology
Other
Product Catalog |
CDK2, Human, Monoclonal Antibody : Trial SizeCode No: MK-13-3S
Target:
Cdk2 Background:
Cellular proliferation is controlled by a family of protein kinases in which the catalytic subunits are members of the cyclin-dependent kinase (cdk) family and the regulatory subunits are cyclins. To date, nine distinct Cdks in addition to eight different cyclins have been identified, in which different CDK/cyclin combinations serve to regulate distinct points in the mammalian cell division cycle. Although Cdc2Hs (Cdk1)/cyclin B controls the transition of cells from the G2 to M-phase, the activities of Cdk2/cyclin E and Cdk2/cyclin A are critical for G1/S-phase transition and progression through S-phase.
Size:
10 µg
Application:
WB
Clone Number:
8A12
Concentration:
0.2 mg/mL
Product Type:
Primary Antibody
Host Species:
Mouse
Species Reactivities:
Human
Species Reactivities:
Mouse
Isotype:
IgG1
Storage Temp. (°C):
4
Shipping Temp. (°C):
4 References:
1) Elledge, S. J., et al. EMBO J. 10, 2653- 2659 (1991) Formulation:
10 g IgG in 50 L volume of PBS containing 1% BSA, 0.2% sucrose and 0.1% sodium azide as preservative. Sodium azide has been reported to form potentially explosive lead or copper azide in plumbing. To prevent forming of these compounds, flush drains enough after disposing of solutions containing sodium azide.
Reactivity:
This antibody recognizes Human Cdk2 and Human Cdk5 and does not recognize Human Cdc2 (Cdk1) on Western blotting. The antibody reacts with the Human and Mouse Cdk2.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
