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Product Catalog |
CDK7 Monoclonal Antibody : Trial SizeCode No: K0068-3S
Target:
Cdk7 Background:
Cyclin-dependent kinase 7 (Cdk7) functions in two essential cellular processes: transcrIPPtion and cell cycle regulation. The 40-42 kDa Cdk7 is the catalytic subunit of the Cdk-Activating Kinase (CAK), the enzyme responsible for phosphorylating and activating many Cdks controlling cell cycle progression, including Cdc2 and Cdk2. Additionally, Cdk7 and its partner Cyclin H are involved in transcrIPPtional regulation, since Cdk7 is the kinase subunit of the general transcrIPPtion factor TFIIH that phosphorylates the C-terminal domain of RNA polymerase II. Hence, Cdk7 may provide a link between cell-cycle control and transcrIPPtional regulation.
Size:
10 µg
Application:
WB
Application:
IPP
Application:
IHC
Clone Number:
MO-1
Concentration:
0.2 mg/mL
Product Type:
Primary Antibody
Host Species:
Mouse
Species Reactivities:
Human
Species Reactivities:
Rat
Isotype:
IgG2b
Storage Temp. (°C):
4
Shipping Temp. (°C):
4 References:
1) Tassan J.P., et al. J. Cell. Biol. 127, 467-478 (1994) Formulation:
10 g IgG in 50 L volume of PBS containing 1% BSA , 10% glycerol and 0.09% NaN3.*Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain.
Reactivity:
This antibody reacts with human and rat Cdk7 on Western blotting, ImmunoprecIPPitation and Immunohistochemistry.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
