SLC7A10/Asc-1

Code No: BMP056
Datasheet: 
Target: 

SLC7A10/Asc-1

Background: 

SLC7A10, also known as Asc-type amino acid transporter 1 (Asc-1), is a member of the cationic amino acid transporter/glycoprotein-associated family. It functions, in association with the cell surface glycoprotein SLC3A2/4F2hc/CD98, as a sodium-independent high-affinity transporter for small neutral amino acids, particularly, D-serine. The SLC7A10 protein has been observed in various tissues including the brain, kidney, heart, liver, lung, pancreas, placenta, and skeletal muscle. Knockout of the slc7a10 gene in mice causes tremors, ataxia, and seizures that result in early postnatal death.

Size: 
100 uL
Application: 
IHC
Application: 
IC
Application: 
FCM
Clone Number: 
Polyclonal
Product Type: 
Primary Antibody
Species Reactivities: 
Human
Storage Temp. (°C): 
-20
References: 

Rutter, A. R., et al., Eur. J. Neurosci. 25, 1757-1766 (2007)
Fukasawa, Y., et al., J. Biol. Chem. 275, 9690-9698 (2000)
Nakauchi, J., et al., Neurosci. Lett. 287, 231-235 (2000)

Formulation: 
100 uL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Reactivity: 
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including the brain by Immunohistochemistry. The reactivity has been confirmed by Immunocytochemistry and intracellular Flow cytometry to detect the full length of human SLC7A10 transiently expressed in HEK 293T cells.
Intended Use: 
For Research use only. Not for use in diagnostic procedure.