SLC6A14, also known as ATB0+, is a member of the Na+ - and Cl- - dependent neurotransmitter transporter family, and is highly expressed in the lung, fetal lung, trachea, and salivary gland. SLC6A14 transports both neutral and cationic amino acids, and has about 60% amino acid similarity with the glycine transporters GLYT1 and GLYT2. The blockade of ATB0+ in cancer cell lines is associated with cell cycle arrest, indicating the potential of ATB0+ as a drug target in cancer chemotherapy.