SLC6A6/TAUT
Code No: BMP046
Background:
SLC6A6, also known as TAUT, belongs to the neurotransmitter transporter family and transports taurine in a Na+- and Cl–-dependent manner. Taurine is involved in many important physiological processes, including antioxidation, osmolarity regulation, and proper maintenance of the functions of the liver and skeletal muscles. Since fetuses and neonates cannot independently synthesize taurine, they depend on taurine supplied through the placenta and breast milk of their mothers for their development. According to a recent report, rat SLC6A6 also appears to transport another neurotransmitter, namely, GABA, across the inner blood-retinal barrier.
Product Type:
Primary Antibody
Species Reactivities:
Human
References:
1) Tomi, M., et al., Biochim. Biophys. Acta. 1778, 2138-2142 (2008) 2) Ito, T., et al., J. Mol. Cell Cardiol. 44, 927-937 (2008) 3) Warskulat, U., et al., Methods Enzymol. 428, 439-458 (2007) 4) Ramamoorthy, S., et al., Biochem. J. 300, 893-900 (1994) 5) Uchida, S., et al., PNAS 89, 8230-8234 (1992)
Formulation:
50 uL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Reactivity:
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including cerebral cortex by Immunohistochemistry. The reactivity has been confirmed by Immunocytochemistry, and intracellular Flow cytometry to detect the full length of human SLC6A6 transiently expressed in HEK 293T cells.
Intended Use:
For Research use only. Not for use in diagnostic procedure.
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