Solutions for Life Science & Diagnostics
Anti-TRAF6 (Mouse) pAb
Additional Information
Anti-TRAF6 (Mouse) pAb Specifications
| Background: | The TRAF-C domain is involved in homotypic and heterotypic aggregation of TRAFs and in interaction of the TNF-receptor superfamily. TRAF6 cDNA has been identified as sequences homologous to the TRAF-C domain of TRAF2 and as binding the cytoplasmic tail of CD40 using the yeast two hybrid system. TRAF6 has a TRAF domain in its carboxyl terminus and has a RING finger domain, a cluster of zinc fingers and a coiled-coil domain. TRAF6 interacts strongly with itself, and weakly with both TRAF2 and TRAF3. Overexpression of TRAF6 activates NF-ï«B. TRAF6 is likely to be a component of the signaling cascade that starts at the IL-1ï¢ receptor and results in the activation of NF-ï«B. |
| Clonality: | Polyclonal |
| Formulation: | In PBS /50% glycerol, pH 7.2 |
| Gene ID Human: | 7189 |
| Gene ID Mouse: | 22034 |
| Host Species: | Rabbit |
| Immunogen: | Recombinant Mouse TRAF6 N-terminal (1-305 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | TRAF6 |
Applications: WB, IP
| IPP: | 2-4 ug/100-500 uL of cell extract from 5x106< |
| WB: | 1:1,000 (for chemiluminescence detection system) |
There are no references for Anti-TRAF6 (Mouse) pAb at this time.
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