Product Type:
Primary Antibody
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
MBL's HA tagged Protein PURIFICATION KIT is designed for the isolation of HA tagged protein from cell culture supernatants containing serum and cell lysate under neutral pH condition. Severe conditions such as acidic or alkaline elution denature protein structure. However, a neutral pH elution can preserve protein activity and native conformation. MBL has developed the Anti-HA tag Beads to purify HA tagged proteins quickly and efficiently. As the Beads can be used at neutral pH, the purified proteins can maintain the activity and conformation. The elution of HA tagged proteins from the Beads is achieved by the addition of the HA peptide. As the HA peptide competes with HA tagged proteins on the Beads, the purified proteins do not lose the protein activity. Using a Spin Column resulting in high efficiency has optimized the simple procedure of this kit.
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
MBL’s HA tagged Protein PURIFICATION KIT is designed for the isolation of HA tagged protein from cell culture supernatants containing serum and cell lysate under neutral pH condition. Severe conditions such as acidic or alkaline elution denature protein structure. However, a neutral pH elution can preserve protein activity and native conformation. MBL has developed the Anti-HA tag Beads to purify HA tagged proteins quickly and efficiently. As the Beads can be used at neutral pH, the purified proteins can maintain the activity and conformation. The elution of HA tagged proteins from the Beads is achieved by the addition of the HA peptide. As the HA peptide competes with HA tagged proteins on the Beads, the purified proteins do not lose the protein activity. Using a Spin Column resulting in high efficiency has optimized the simple procedure of this kit.
Related Products:
PM054 anti--Tubulin (polyclonal)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Size:
1 mL x 1 (10 tests)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Size:
15 mL x 1 (150 tests)
Related Products:
PM053 anti--Actin (polyclonal)
References:
Hall, J. L., and Cowan, N. J., Nucleic Acids Res. 13, 207-223 (1985)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Size:
15 mL x 3 (450 tests)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
Eukaryotic translation initiation factor 2C, subunit 2 (EIF2C2; AGO2), is a member of the argonaute protein family. It is a core component of RNA-induced silencing complex (RISC). The EIF2C2 belonging to the human argonaute protein family possesses endonuclease activity and functions as a slicer in gene silencing pathways. It recognizes and cleaves target mRNA by RNA interference. In small interference RNA (siRNA) pathway, EIF2C2 forms a complex with EIF2C1 and siRNA, and in microRNA (miRNA) pathway, it binds EIF2C3 to miRNA. EIF2C2 expression is controlled by epidermal growth factor receptor and mitogen-activated protein kinase signaling in human breast cancer cell line.
Product Type:
Primary Antibody
Related Products:
RN002P Anti-EIF4G1 (polyclonal)
RN003P Anti-EIF4G2 (polyclonal)
RN004P Anti-ELAVL1/HuR (polyclonal)
RN005P Anti-ELAVL2/HuB (polyclonal)
RN006P Anti-ELAVL3/HuC (polyclonal)
RN007P Anti-IGF2BP1/IMP1 (polyclonal)
RN008P Anti-IGF2BP2/IMP2 (polyclonal)
RN009P Anti-IGF2BP3/IMP3 (polyclonal)
RN010P Anti-MSI1/Musashi1 (polyclonal)
References:
Adams, B. D., et al., Endocrinology 150, 14-23 (2009)
Chi, S. W., et al., Nature 460, 479-486 (2009)
Azuma-Mukai, A., et al., PNAS 105, 7964-7969 (2008)
O’Carroll, D., et al., Genes & Dev. 21, 1999-2004 (2007)
Liu, J., et al., Science 305, 1437-1441 (2004)RN001PK RIP-Assay Starter Kit EIF4E (polyclonal)
RN002PK RIP-Assay Starter Kit EIF4G1 (polyclonal)
RN003PK RIP-Assay Starter Kit EIF4G2 (polyclonal)
RN004PK RIP-Assay Starter Kit ELAVL1/HuR (polyclonal)
RN005PK RIP-Assay Starter Kit ELAVL2/HuB (polyclonal)
RN006PK RIP-Assay Starter Kit ELAVL3/HuC (polyclonal)
RN007PK RIP-Assay Starter Kit IGF2BP1/IMP1 (polyclonal)
RN008PK RIP-Assay Starter Kit IGF2BP2/IMP2 (polyclonal)
RN009PK RIP-Assay Starter Kit IGF2BP3/IMP3 (polyclonal)
RN010PK RIP-Assay Starter Kit MSI1/Musashi1 (polyclonal)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.
Product Type:
Primary Antibody
Related Products:
M169-3 anti-mouse Neuropilin-1/CD304 (N43-7)
M169-A48 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 488
M169-A64 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 647
M120-3 anti-Foxp3 (99D04)
PM024 anti-Foxp3 (polyclonal)
PM024S anti-Foxp3 (polyclonal)
D237-3 anti-Foxp3 (MF-14)
D237-4 anti-Foxp3-FITC (MF-14)
D237-6 anti-Foxp3-Biotin (MF-14)
D239-3 anti-FR4 (TH6)
D239-4 anti-FR4-FITC (TH6)
D239-5 anti-FR4-PE (TH6)
D239-6 anti-FR4-Biotin (TH6)
D222-3 anti-mouse GITR (DTA-1)
D222-4 anti-mouse GITR-FITC (DTA-1)
D222-5 anti-mouse GITR-PE (DTA-1)
References:
Sarris, M., et al., Immunity 28, 402-413 (2008)
Bruder, D., et al., Eur. J. Immunol. 34, 623-630 (2004)
Soker, S., et al., Cell 92, 735-745 (1998)
He, Z., and Tessier-Lavigne, M., Cell 90, 739-751 (1997)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.
Product Type:
Primary Antibody
Related Products:
M169-3 anti-mouse Neuropilin-1/CD304 (N43-7)
M169-A48 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 488
M169-A64 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 647
M120-3 anti-Foxp3 (99D04)
PM024 anti-Foxp3 (polyclonal)
PM024S anti-Foxp3 (polyclonal)
D237-3 anti-Foxp3 (MF-14)
D237-4 anti-Foxp3-FITC (MF-14)
D237-6 anti-Foxp3-Biotin (MF-14)
D239-3 anti-FR4 (TH6)
D239-4 anti-FR4-FITC (TH6)
D239-5 anti-FR4-PE (TH6)
D239-6 anti-FR4-Biotin (TH6)
D222-3 anti-mouse GITR (DTA-1)
D222-4 anti-mouse GITR-FITC (DTA-1)
D222-5 anti-mouse GITR-PE (DTA-1)
References:
Sarris, M., et al., Immunity 28, 402-413 (2008)
Bruder, D., et al., Eur. J. Immunol. 34, 623-630 (2004)
Soker, S., et al., Cell 92, 735-745 (1998)
He, Z., and Tessier-Lavigne, M., Cell 90, 739-751 (1997)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
Background:
Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.
Product Type:
Primary Antibody
Related Products:
M169-3 anti-mouse Neuropilin-1/CD304 (N43-7)
M169-A48 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 488
M169-A64 anti-mouse Neuropilin-1/CD304 (N43-7)-Alexa Fluor® 647
M120-3 anti-Foxp3 (99D04)
PM024 anti-Foxp3 (polyclonal)
PM024S anti-Foxp3 (polyclonal)
D237-3 anti-Foxp3 (MF-14)
D237-4 anti-Foxp3-FITC (MF-14)
D237-6 anti-Foxp3-Biotin (MF-14)
D239-3 anti-FR4 (TH6)
D239-4 anti-FR4-FITC (TH6)
D239-5 anti-FR4-PE (TH6)
D239-6 anti-FR4-Biotin (TH6)
D222-3 anti-mouse GITR (DTA-1)
D222-4 anti-mouse GITR-FITC (DTA-1)
D222-5 anti-mouse GITR-PE (DTA-1)
References:
Sarris, M., et al., Immunity 28, 402-413 (2008)
Bruder, D., et al., Eur. J. Immunol. 34, 623-630 (2004)
Soker, S., et al., Cell 92, 735-745 (1998)
He, Z., and Tessier-Lavigne, M., Cell 90, 739-751 (1997)
Intended Use:
For Research use only. Not for use in diagnostic procedure.
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